Efficient gene silencing by delivery of locked nucleic acid antisense oligonucleotides, unassisted by transfection reagents

For the past 15–20 years, the intracellular delivery and silencing activity of oligodeoxynucleotides have been essentially completely dependent on the use of a delivery technology (e.g. lipofection). We have developed a method (called ‘gymnosis’) that does not require the use of any transfection rea...

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Bibliografske podrobnosti
Main Authors: Stein, C. A., Hansen, J. Bo, Lai, Johnathan, Wu, SiJian, Voskresenskiy, Anatoliy, Høg, Anja, Worm, Jesper, Hedtjärn, Maj, Souleimanian, Naira, Miller, Paul, Soifer, Harris S., Castanotto, Daniella, Benimetskaya, Luba, Ørum, Henrik, Koch, Troels
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2010
Teme:
Methods Online
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2800216/
https://ncbi.nlm.nih.gov/pubmed/19854938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp841
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