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Longitudinal assessment of tumor development using cancer avatars derived from genetically engineered pluripotent stem cells
Many cellular models aimed at elucidating cancer biology do not recapitulate pathobiology including tumor heterogeneity, an inherent feature of cancer that underlies treatment resistance. Here we introduce a cancer modeling paradigm using genetically engineered human pluripotent stem cells (hiPSCs)...
Gorde:
| Argitaratua izan da: | Nat Commun |
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| Egile Nagusiak: | , , , , , , , , , , , , , , , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Nature Publishing Group UK
2020
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6987220/ https://ncbi.nlm.nih.gov/pubmed/31992716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14312-1 |
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