TMOD-09. MODELING TERT PROMOTER MUTATION IN ISOGENIC NEXT GENERATION GBM MODELS

Telomere reverse transcriptase (TERT) promotor mutations increase TERT expression and are known to be the most common single genetic abnormality in Glioblastoma (GBM). Recent studies have revealed this mutation to be an early event in gliomagenesis but it is detected subclonally in a considerable nu...

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Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: Miki, Shunichiro, Koga, Tomoyuki, Parisian, Alison, Furnari, Frank
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Tumor Models
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6846790/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.1108
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