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ATRT-02. INTERACTIONS BETWEEN SMARCB1 AND CELLULAR DIFFERENTIATION STATE IN THE GENESIS OF ATYPICAL TERATOID RHABDOID TUMORS

Atypical teratoid rhabdoid tumors (ATRT) are challenging pediatric brain tumors which are predominantly associated with inactivation of the gene SMARCB1 (aka INI1). As SMARCB1 is a conserved subunit of the chromatin remodeling BAF complex, we hypothesize that the effect of its loss of function is in...

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Pubblicato in:Neuro Oncol
Autori principali: Parisian, Alison, Koga, Tomoyuki, Furnari, Frank
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474970/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.001
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