ATRT-06. SMARCB1 LOSS DRIVEN NON-CANONICAL PRC1 ACTIVITY REGULATES DIFFERENTIATION IN ATYPICAL TERATOID RHABDOID TUMORS (ATRT)

Loss of SMARCB1 is the hallmark genetic event that characterizes ATRT. SMARCB1 is a member of the SWI/SNF chromatin remodeling complex that is responsible for determining cellular pluripotency and lineage commitment. To identify co-operating epigenetic factors, we performed an unbiased shRNA screen...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Neuro Oncol
मुख्य लेखकों: Alimova, Irina, Danis, Etienne, Weetall, Marla, Pierce, Angela M, Wang, Dong, Serkova, Natalie, Balakrishnan, Ilango, Madhavan, Krishna, Sanford, Bridget, Michel, Cole, Foreman, Nicholas K, Baird, John, Venkataraman, Sujatha, Vibhakar, Rajeev
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Oxford University Press 2020
विषय:
Atypical Teratoid/Rhabdoid Tumors
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715494/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.006
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