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ATRT-06. ISPINESIB IS AN EFFICACIOUS THERAPEUTIC AGENT FOR ATYPICAL TERATOID RHABDOID TUMORS
BACKGROUND: Atypical teratoid rhabdoid tumor (ATRT) is an aggressive and deadly embryonal brain tumor in children. KIF11 is needed for formation of the bipolar spindle in metaphase. KIF11 suppression leads to prolonged mitotic arrest and subsequent cell death in mitosis. KIF11 inhibitors are current...
Gardado en:
| Publicado en: | Neuro Oncol |
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| Main Authors: | , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6477369/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.005 |
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