TMOD-28. AUTHENTIC HUMAN GLIOMA MODELING USING GENETICALLY ENGINEERED INDUCED PLURIPOTENT STEM CELLS

Many mouse and human glioma models have been utilized to study the genetic alterations involved in the genesis of these tumors, but they have not been fully evaluated for how closely they recapitulate pathobiology, including tumor heterogeneity, which is an inherent feature making patient treatment...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Koga, Tomoyuki, Chaim, Isaac, Markmiller, Sebastian, Benitez, Jorge, Parisian, Alison, Miki, Shunichiro, Hessenauer, Florian, Turner, Kristen, Venneti, Sriram, Malicki, Denise, Wechsler-Reya, Robert, Mischel, Paul, Chen, Clark, Yeo, Gene, Furnari, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Tumor Models
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6846083/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.1127
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