TMOD-42. CRISPR/Cas9-EDITED HUMAN NEURAL STEM CELLS GIVE RISE TO BRAIN TUMORS RESEMBLING GLIOBLASTOMAS

Glioblastoma is the most malignant tumor of the brain with a median overall survival of 12-15 months. One of the factors that make the treatment of this disease difficult is its inherent and typical heterogeneity promoted by different genetic drivers. Here we show that neural stem cells (NSCs) deriv...

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Publicado en:Neuro Oncol
Autores principales: Koga, Tomoyuki, Benitez, Jorge, Markmiller, Sebastian, D’Antonio, Matteo, Parisian, Alison, Saberi, Shahram, Turner, Kristen, Hessenauer, Matthias-Florian, Thorne, Amy Haseley, Zanca, Ciro, Mischel, Paul, Frazer, Kelly, Yeo, Gene, Cavenee, Webster, Furnari, Frank
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692077/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.1078
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