TMOD-42. CRISPR/Cas9-EDITED HUMAN NEURAL STEM CELLS GIVE RISE TO BRAIN TUMORS RESEMBLING GLIOBLASTOMAS

Glioblastoma is the most malignant tumor of the brain with a median overall survival of 12-15 months. One of the factors that make the treatment of this disease difficult is its inherent and typical heterogeneity promoted by different genetic drivers. Here we show that neural stem cells (NSCs) deriv...

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izdano v:Neuro Oncol
Main Authors: Koga, Tomoyuki, Benitez, Jorge, Markmiller, Sebastian, D’Antonio, Matteo, Parisian, Alison, Saberi, Shahram, Turner, Kristen, Hessenauer, Matthias-Florian, Thorne, Amy Haseley, Zanca, Ciro, Mischel, Paul, Frazer, Kelly, Yeo, Gene, Cavenee, Webster, Furnari, Frank
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2017
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Abstracts
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692077/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.1078
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