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OTEH-9. scRNA sequencing of proneural GBM avatar model reveals acquisition of oncogenic transcriptional programming and infers a developmental path towards a genomically unstable state

Glioblastomas (GBMs) are the most common malignant primary brain tumors, and the paucity of novel treatments warrants an investigation of its origins and development into aggressive, lethal tumors. Koga & Chaim et al. have recently shown that human pluripotent stem cells (hiPSCs) with different...

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Detalles Bibliográficos
Publicado en:Neurooncol Adv
Main Authors: Taylor, Brett M, Chaim, Isaac A, Koga, Tomoyuki, Miki, Shunichiro, Yee, Brian E, Yeo, Gene W, Furnari, Frank B
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8255420/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdab070.048
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