OTEH-9. scRNA sequencing of proneural GBM avatar model reveals acquisition of oncogenic transcriptional programming and infers a developmental path towards a genomically unstable state

Glioblastomas (GBMs) are the most common malignant primary brain tumors, and the paucity of novel treatments warrants an investigation of its origins and development into aggressive, lethal tumors. Koga & Chaim et al. have recently shown that human pluripotent stem cells (hiPSCs) with different...

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Detaylı Bibliyografya
Yayımlandı:Neurooncol Adv
Asıl Yazarlar: Taylor, Brett M, Chaim, Isaac A, Koga, Tomoyuki, Miki, Shunichiro, Yee, Brian E, Yeo, Gene W, Furnari, Frank B
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2021
Konular:
Supplement Abstracts
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8255420/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdab070.048
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