Enterococcus faecalis exploits the human fibrinolytic system to drive excess collagenolysis: implications in gut healing and identification of druggable targets

Perforations, anastomotic leak, and subsequent intra-abdominal sepsis are among the most common and feared complications of invasive interventions in the colon and remaining intestinal tract. During physiological healing, tissue protease activity is finely orchestrated to maintain the strength and i...

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Détails bibliographiques
Publié dans:Am J Physiol Gastrointest Liver Physiol
Auteurs principaux: Jacobson, Richard A., Wienholts, Kiedo, Williamson, Ashley J., Gaines, Sara, Hyoju, Sanjiv, van Goor, Harry, Zaborin, Alexander, Shogan, Benjamin D., Zaborina, Olga, Alverdy, John C.
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2020
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985841/
https://ncbi.nlm.nih.gov/pubmed/31604031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00236.2019
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