Novel de novo synthesized phosphate carrier compound ABA-PEG20k-Pi20 suppresses collagenase production in Enterococcus faecalis and prevents colonic anastomotic leak in an experimental model

BACKGROUND: Previous work has demonstrated that anastomotic leak can be caused by collagenolytic bacteria such as Enterococcus faecalis via an effect on wound collagen. In humans, E. faecalis is the organism cultured most commonly from a leaking anastomosis, and is not routinely eliminated by standa...

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Detalhes bibliográficos
Publicado no:Br J Surg
Main Authors: Wiegerinck, M, Hyoju, S K, Mao, J, Zaborin, A, Adriaansens, C, Salzman, E, Hyman, N H, Zaborina, O, van Goor, H, Alverdy, J C
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6827486/
https://ncbi.nlm.nih.gov/pubmed/29658991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bjs.10859
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