Novel de novo synthesized phosphate carrier compound ABA-PEG20k-Pi20 suppresses collagenase production in Enterococcus faecalis and prevents colonic anastomotic leak in an experimental model

BACKGROUND: Previous work has demonstrated that anastomotic leak can be caused by collagenolytic bacteria such as Enterococcus faecalis via an effect on wound collagen. In humans, E. faecalis is the organism cultured most commonly from a leaking anastomosis, and is not routinely eliminated by standa...

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Vydáno v:Br J Surg
Hlavní autoři: Wiegerinck, M, Hyoju, S K, Mao, J, Zaborin, A, Adriaansens, C, Salzman, E, Hyman, N H, Zaborina, O, van Goor, H, Alverdy, J C
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6827486/
https://ncbi.nlm.nih.gov/pubmed/29658991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bjs.10859
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