Oral polyphosphate suppresses bacterial collagenase production and prevents anastomotic leak due to Serratia marcescens and Pseudomonas aeruginosa

OBJECTIVE: The objective of this study was to determine the effect of polyphosphate on intestinal bacterial collagenase production and anastomotic leak in mice undergoing colon surgery. SUMMARY BACKGROUND DATA: We have previously shown that anastomotic leak can be caused by intestinal pathogens that...

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Publicat a:Ann Surg
Autors principals: Hyoju, Sanjiv K., Klabbers, Robin, Aaron, Melissa, Krezalek, Monika A., Zaborin, Alexander, Wiegerinck, Mara, Hyman, Neil H., Zaborina, Olga, Van Goor, Harry, Alverdy, John C
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5540820/
https://ncbi.nlm.nih.gov/pubmed/28166091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SLA.0000000000002167
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