Enterococcus faecalis exploits the human fibrinolytic system to drive excess collagenolysis: implications in gut healing and identification of druggable targets

Perforations, anastomotic leak, and subsequent intra-abdominal sepsis are among the most common and feared complications of invasive interventions in the colon and remaining intestinal tract. During physiological healing, tissue protease activity is finely orchestrated to maintain the strength and i...

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Опубликовано в: :Am J Physiol Gastrointest Liver Physiol
Главные авторы: Jacobson, Richard A., Wienholts, Kiedo, Williamson, Ashley J., Gaines, Sara, Hyoju, Sanjiv, van Goor, Harry, Zaborin, Alexander, Shogan, Benjamin D., Zaborina, Olga, Alverdy, John C.
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2020
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985841/
https://ncbi.nlm.nih.gov/pubmed/31604031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00236.2019
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