Enterococcus faecalis exploits the human fibrinolytic system to drive excess collagenolysis: implications in gut healing and identification of druggable targets

Perforations, anastomotic leak, and subsequent intra-abdominal sepsis are among the most common and feared complications of invasive interventions in the colon and remaining intestinal tract. During physiological healing, tissue protease activity is finely orchestrated to maintain the strength and i...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Am J Physiol Gastrointest Liver Physiol
Prif Awduron: Jacobson, Richard A., Wienholts, Kiedo, Williamson, Ashley J., Gaines, Sara, Hyoju, Sanjiv, van Goor, Harry, Zaborin, Alexander, Shogan, Benjamin D., Zaborina, Olga, Alverdy, John C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Physiological Society 2020
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985841/
https://ncbi.nlm.nih.gov/pubmed/31604031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00236.2019
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