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Exploiting CRISPR-Cas to manipulate Enterococcus faecalis populations

CRISPR-Cas provides a barrier to horizontal gene transfer in prokaryotes. It was previously observed that functional CRISPR-Cas systems are absent from multidrug-resistant (MDR) Enterococcus faecalis, which only possess an orphan CRISPR locus, termed CRISPR2, lacking cas genes. Here, we investigate...

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Bibliografske podrobnosti
izdano v:eLife
Main Authors: Hullahalli, Karthik, Rodrigues, Marinelle, Palmer, Kelli L
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5491264/
https://ncbi.nlm.nih.gov/pubmed/28644125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.26664
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