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Molecular Targets and Therapeutic Strategies in Spinocerebellar Ataxia Type 7

Spinocerebellar ataxia type 7 (SCA7) is a rare autosomal dominant neurodegenerative disorder characterized by progressive neuronal loss in the cerebellum, brainstem, and retina, leading to cerebellar ataxia and blindness as major symptoms. SCA7 is due to the expansion of a CAG triplet repeat that is...

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Bibliografske podrobnosti
izdano v:Neurotherapeutics
Main Authors: Niewiadomska-Cimicka, Anna, Trottier, Yvon
Format: Artigo
Jezik:Inglês
Izdano: Springer International Publishing 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985300/
https://ncbi.nlm.nih.gov/pubmed/31432449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-019-00778-5
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