SCA8 CAG/CTG Expansions, a Tale of Two TOXICities: A Unique or Common Case?

por Merienne, Karine, Trottier, Yvon
Publicado 2009

Molecular Targets and Therapeutic Strategies in Spinocerebellar Ataxia Type 7

por Niewiadomska-Cimicka, Anna, Trottier, Yvon
Publicado en Neurotherapeutics (2019)

Gene Deregulation and Underlying Mechanisms in Spinocerebellar Ataxias With Polyglutamine Expansion

por Niewiadomska-Cimicka, Anna, Hache, Antoine, Trottier, Yvon
Publicado en Front Neurosci (2020)

Transcriptional Activation of REST by Sp1 in Huntington's Disease Models

por Ravache, Myriam, Weber, Chantal, Mérienne, Karine, Trottier, Yvon
Publicado 2010

Targeting expression of expanded polyglutamine proteins to the endoplasmic reticulum or mitochondria prevents their aggregation

por Rousseau, Erwann, Dehay, Benjamin, Ben-Haïem, Léa, Trottier, Yvon, Morange, Michel, Bertolotti, Anne
Publicado 2004

PREVENTING POLYGLUTAMINE-INDUCED ACTIVATION OF C-JUN DELAYS NEURONAL DYSFUNCTION IN A MOUSE MODEL OF SCA7 RETINOPATHY

por Merienne, Karine, Friedman, James, Akimoto, Masayuki, Abou-Sleymane, Gretta, Weber, Chantal, Swaroop, Anand, Trottier, Yvon
Publicado 2006

Transcription Elongation and Tissue-Specific Somatic CAG Instability

por Goula, Agathi-Vasiliki, Stys, Agnieszka, Chan, Jackson P. K., Trottier, Yvon, Festenstein, Richard, Merienne, Karine
Publicado 2012

Stoichiometry of Base Excision Repair Proteins Correlates with Increased Somatic CAG Instability in Striatum over Cerebellum in Huntington's Disease Transgenic Mice

por Goula, Agathi-Vassiliki, Berquist, Brian R., Wilson, David M., Wheeler, Vanessa C., Trottier, Yvon, Merienne, Karine
Publicado 2009

Molecular characterization of Hepatitis E virus detected in swine farms in the province of Quebec

por Ward, Pierre, Müller, Peter, Letellier, Ann, Quessy, Sylvain, Simard, Carole, Trottier, Yvon-Louis, Houde, Alain, Brassard, Julie
Publicado 2008

Disease Progression Despite Early Loss of Polyglutamine Protein Expression in SCA7 Mouse Model

por Helmlinger, Dominique, Abou-Sleymane, Gretta, Yvert, Gaël, Rousseau, Stéphane, Weber, Chantal, Trottier, Yvon, Mandel, Jean-Louis, Devys, Didier
Publicado en J Neurosci (2004)

PML clastosomes prevent nuclear accumulation of mutant ataxin-7 and other polyglutamine proteins

por Janer, Alexandre, Martin, Elodie, Muriel, Marie-Paule, Latouche, Morwena, Fujigasaki, Hiroto, Ruberg, Merle, Brice, Alexis, Trottier, Yvon, Sittler, Annie
Publicado 2006

Nucleotide sequence, DNA damage location and protein stoichiometry influence base excision repair outcome at CAG/CTG repeats

por Goula, Agathi-Vasiliki, Pearson, Christopher E., Della Maria, Julie, Trottier, Yvon, Tomkinson, Alan E., Wilson, David M., Merienne, Karine
Publicado 2012

Microbiological contamination in counterfeit and unapproved drugs

por Pullirsch, Dieter, Bellemare, Julie, Hackl, Andreas, Trottier, Yvon-Louis, Mayrhofer, Andreas, Schindl, Heidemarie, Taillon, Christine, Gartner, Christian, Hottowy, Brigitte, Beck, Gerhard, Gagnon, Jacques
Publicado 2014

An Isoform of Ataxin‐3 Accumulates in the Nucleus of Neuronal Cells in Affected Brain Regions of SCA3 Patients

por Schmidt, Thorsten, Landwehrmeyer, G. Bernhard, Schmitt, Ina, Trottier, Yvon, Auburger, Georg, Laccone, Franco, Klockgether, Thomas, Völpel, Michael, Epplen, Jörg T., Schöls, Ludger, Riess, Olaf
Publicado en Brain Pathol (2006)

Glutamine-Expanded Ataxin-7 Alters TFTC/STAGA Recruitment and Chromatin Structure Leading to Photoreceptor Dysfunction

por Helmlinger, Dominique, Hardy, Sara, Abou-Sleymane, Gretta, Eberlin, Adrien, Bowman, Aaron B, Gansmüller, Anne, Picaud, Serge, Zoghbi, Huda Y, Trottier, Yvon, Tora, Làszlò, Devys, Didier
Publicado 2006

Structure of a Single-Chain Fv Bound to the 17 N-Terminal Residues of Huntingtin Provides Insights into Pathogenic Amyloid Formation and Suppression

por De Genst, Erwin, Chirgadze, Dimitri Y., Klein, Fabrice A.C., Butler, David C., Matak-Vinković, Dijana, Trottier, Yvon, Huston, James S., Messer, Anne, Dobson, Christopher M.
Publicado en J Mol Biol (2015)

Proteolysis of Mutant Huntingtin Produces an Exon 1 Fragment That Accumulates as an Aggregated Protein in Neuronal Nuclei in Huntington Disease

por Landles, Christian, Sathasivam, Kirupa, Weiss, Andreas, Woodman, Ben, Moffitt, Hilary, Finkbeiner, Steve, Sun, Banghua, Gafni, Juliette, Ellerby, Lisa M., Trottier, Yvon, Richards, William G., Osmand, Alex, Paganetti, Paolo, Bates, Gillian P.
Publicado 2010

SCA7 Mouse Cerebellar Pathology Reveals Preferential Downregulation of Key Purkinje Cell-Identity Genes and Shared Disease Signature with SCA1 and SCA2

por Niewiadomska-Cimicka, Anna, Doussau, Frédéric, Perot, Jean-Baptiste, Roux, Michel J., Keime, Celine, Hache, Antoine, Piguet, Françoise, Novati, Ariana, Weber, Chantal, Yalcin, Binnaz, Meziane, Hamid, Champy, Marie-France, Grandgirard, Erwan, Karam, Alice, Messaddeq, Nadia, Eisenmann, Aurélie, Brouillet, Emmanuel, Nguyen, Hoa Huu Phuc, Flament, Julien, Isope, Philippe, Trottier, Yvon
Publicado en J Neurosci (2021)

Phenotypic Characterization of Individuals with 30–40 CAG Repeats in the Huntington Disease (HD) Gene Reveals HD Cases with 36 Repeats and Apparently Normal Elderly Individuals wit...

por Rubinsztein, David C., Leggo, Jayne, Coles, Rhian, Almqvist, Elisabeth, Biancalana, Valerie, Cassiman, Jean-Jacques, Chotai, Kokila, Connarty, Margaret, Craufurd, David, Curtis, Anne, Curtis, Diana, Davidson, Mark J., Differ, Anne-Marie, Dode, Catherine, Dodge, Alan, Frontali, Marina, Ranen, Neal G., Stine, O. Colin, Sherr, Meeia, Abbott, Margaret H., Franz, Mary L., Graham, Colin A., Harper, Peter S., Hedreen, John C., Jackson, Anthony, Kaplan, Jean-Claude, Losekoot, Monique, MacMillan, John C., Morrison, Patrick, Trottier, Yvon, Novelletto, Andrea, Simpson, Sheila A., Theilmann, Jane, Whittaker, Joanne L., Folstein, Susan E., Ross, Christopher A., Hayden, Michael R.
Publicado 1996