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Transcription Elongation and Tissue-Specific Somatic CAG Instability
The expansion of CAG/CTG repeats is responsible for many diseases, including Huntington's disease (HD) and myotonic dystrophy 1. CAG/CTG expansions are unstable in selective somatic tissues, which accelerates disease progression. The mechanisms underlying repeat instability are complex, and it...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3510035/ https://ncbi.nlm.nih.gov/pubmed/23209427 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003051 |
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