Transcription Elongation and Tissue-Specific Somatic CAG Instability

The expansion of CAG/CTG repeats is responsible for many diseases, including Huntington's disease (HD) and myotonic dystrophy 1. CAG/CTG expansions are unstable in selective somatic tissues, which accelerates disease progression. The mechanisms underlying repeat instability are complex, and it...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Goula, Agathi-Vasiliki, Stys, Agnieszka, Chan, Jackson P. K., Trottier, Yvon, Festenstein, Richard, Merienne, Karine
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510035/
https://ncbi.nlm.nih.gov/pubmed/23209427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003051
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi