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Identifying Therapeutic Targets for Spinocerebellar Ataxia Type 3/Machado–Joseph Disease through Integration of Pathological Biomarkers and Therapeutic Strategies

Spinocerebellar ataxia type 3/Machado–Joseph disease (SCA3/MJD) is a progressive motor disease with no broadly effective treatment. However, most current therapies are based on symptoms rather than the underlying disease mechanisms. In this review, we describe potential therapeutic strategies based...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Chen, Yu-Shuan, Hong, Zhen-Xiang, Lin, Shinn-Zong, Harn, Horng-Jyh
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7246822/
https://ncbi.nlm.nih.gov/pubmed/32357546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21093063
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