Peripheral Oxidative Stress Biomarkers in Spinocerebellar Ataxia Type 3/Machado–Joseph Disease

OBJECTIVES: Spinocerebellar ataxia type 3/Machado–Joseph disease (SCA3/MJD) is a polyglutamine disorder with no current disease-modifying treatment. Conformational changes in mutant ataxin-3 trigger different pathogenic cascades, including reactive oxygen species (ROS) generation; however, the clini...

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書誌詳細
出版年:Front Neurol
主要な著者: de Assis, Adriano M., Saute, Jonas Alex Morales, Longoni, Aline, Haas, Clarissa Branco, Torrez, Vitor Rocco, Brochier, Andressa Wigner, Souza, Gabriele Nunes, Furtado, Gabriel Vasata, Gheno, Tailise Conte, Russo, Aline, Monte, Thais Lampert, Castilhos, Raphael Machado, Schumacher-Schuh, Artur, D’Avila, Rui, Donis, Karina Carvalho, de Mello Rieder, Carlos Roberto, Souza, Diogo Onofre, Camey, Suzi, Leotti, Vanessa Bielefeldt, Jardim, Laura Bannach, Portela, Luis Valmor
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2017
主題:
Neuroscience
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5611390/
https://ncbi.nlm.nih.gov/pubmed/28979235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2017.00485
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