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Mouse Models of Machado-Joseph Disease and Other Polyglutamine Spinocerebellar Ataxias
Summary: Machado-Joseph disease (MJD), also called spinocerebellar ataxia type 3, is caused by mutant ataxin-3 with a polyglutamine expansion. Although there is no treatment available at present to cure or delay the onset of MJD, mouse models have been generated to facilitate the development of a th...
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| Autor principal: | |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Experimental NeuroTherapeutics, Inc.
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1144491/ https://ncbi.nlm.nih.gov/pubmed/16389311 |
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