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Pathological missorting of endogenous MAPT/Tau in neurons caused by failure of protein degradation systems
Missorting of MAPT/Tau represents one of the early signs of neurodegeneration in Alzheimer disease. The triggers for this are still a matter of debate. Here we investigated the sorting mechanisms of endogenous MAPT in mature primary neurons using microfluidic chambers (MFCs) where cell compartments...
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| Опубликовано в: : | Autophagy |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Taylor & Francis
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6984766/ https://ncbi.nlm.nih.gov/pubmed/30145931 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1509607 |
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