Loading...

Combining Chalcones with Donepezil to Inhibit Both Cholinesterases and Aβ Fibril Assembly

The fact that the number of people with Alzheimer’s disease is increasing, combined with the limited availability of drugs for its treatment, emphasize the need for the development of novel effective therapeutics for treating this brain disorder. Herein, we focus on generating 12 chalcone-donepezil...

Full description

Saved in:
Bibliographic Details
Published in:Molecules
Main Authors: Thamban Chandrika, Nishad, Fosso, Marina Y., Tsodikov, Oleg V., LeVine, Harry, Garneau-Tsodikova, Sylvie
Format: Artigo
Language:Inglês
Published: MDPI 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6983213/
https://ncbi.nlm.nih.gov/pubmed/31878304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25010077
Tags: Add Tag
No Tags, Be the first to tag this record!