Cargando...
Multifunctional Donepezil Analogues as Cholinesterase and BACE1 Inhibitors
A series of 22 donepezil analogues were synthesized through alkylation/benzylation and compared to donepezil and its 6-O-desmethyl adduct. All the compounds were found to be potent inhibitors of both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), two enzymes responsible for the hydrol...
Gardado en:
| Publicado en: | Molecules |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
MDPI
2018
|
| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6321525/ https://ncbi.nlm.nih.gov/pubmed/30544832 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23123252 |
| Tags: |
Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|