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Synthesis and Bioactivities of Kanamycin B-Derived Cationic Amphiphiles

Cationic amphiphiles derived from aminoglycosides (AGs) have been shown to exhibit enhanced antimicrobial activity. Through the attachment of hydrophobic residues such as linear alkyl chains on the AG backbone, interesting antibacterial and antifungal agents with a novel mechanism of action have bee...

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Bibliografische gegevens
Gepubliceerd in:J Med Chem
Hoofdauteurs: Fosso, Marina Y., Shrestha, Sanjib K., Green, Keith D., Garneau-Tsodikova, Sylvie
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5154386/
https://ncbi.nlm.nih.gov/pubmed/26592740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.5b01375
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