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Synthesis and Bioactivities of Kanamycin B-Derived Cationic Amphiphiles

Cationic amphiphiles derived from aminoglycosides (AGs) have been shown to exhibit enhanced antimicrobial activity. Through the attachment of hydrophobic residues such as linear alkyl chains on the AG backbone, interesting antibacterial and antifungal agents with a novel mechanism of action have bee...

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Detalles Bibliográficos
Publicado en:J Med Chem
Main Authors: Fosso, Marina Y., Shrestha, Sanjib K., Green, Keith D., Garneau-Tsodikova, Sylvie
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5154386/
https://ncbi.nlm.nih.gov/pubmed/26592740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.5b01375
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