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Amphiphilic Tobramycin Analogues as Antibacterial and Antifungal Agents

In this study, we investigated the in vitro antifungal activities, cytotoxicities, and membrane-disruptive actions of amphiphilic tobramycin (TOB) analogues. The antifungal activities were established by determination of MIC values and in time-kill studies. Cytotoxicity was evaluated in mammalian ce...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Shrestha, Sanjib K., Fosso, Marina Y., Green, Keith D., Garneau-Tsodikova, Sylvie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505213/
https://ncbi.nlm.nih.gov/pubmed/26033722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00229-15
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