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Combining Chalcones with Donepezil to Inhibit Both Cholinesterases and Aβ Fibril Assembly

The fact that the number of people with Alzheimer’s disease is increasing, combined with the limited availability of drugs for its treatment, emphasize the need for the development of novel effective therapeutics for treating this brain disorder. Herein, we focus on generating 12 chalcone-donepezil...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Molecules
Prif Awduron: Thamban Chandrika, Nishad, Fosso, Marina Y., Tsodikov, Oleg V., LeVine, Harry, Garneau-Tsodikova, Sylvie
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6983213/
https://ncbi.nlm.nih.gov/pubmed/31878304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25010077
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