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A review of patents (2011–2015) towards combating resistance to and toxicity of aminoglycosides

Since the discovery of the first aminoglycoside (AG), streptomycin, in 1943, these broad-spectrum antibiotics have been extensively used for the treatment of Gram-negative and Gram-positive bacterial infections. The inherent toxicity (ototoxicity and nephrotoxicity) associated with their long-term u...

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Detalhes bibliográficos
Publicado no:Medchemcomm
Main Authors: Chandrika, Nishad Thamban, Garneau-Tsodikova, Sylvie
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4806794/
https://ncbi.nlm.nih.gov/pubmed/27019689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C5MD00453E
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