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Expanding Aminoglycoside Resistance Enzyme Regiospecificity by Mutation and Truncation
Aminoglycosides (AGs) are broad-spectrum antibiotics famous for their antibacterial activity against Gram-positive and Gram-negative bacteria, as well as mycobacteria. In the United States, the most prescribed AGs, including amikacin (AMK), gentamicin (GEN), and tobramycin (TOB), are vital component...
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| Veröffentlicht in: | Biochemistry |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5174979/ https://ncbi.nlm.nih.gov/pubmed/27618454 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00770 |
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