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Effects of Altering Aminoglycoside Structures on Bacterial Resistance Enzyme Activities

Aminoglycoside-modifying enzymes (AMEs) constitute the most prevalent mechanism of resistance to aminoglycosides by bacteria. We show that aminoglycosides can be doubly modified by the sequential actions of AMEs, with the activity of the second AME in most cases unaffected, decreased, or completely...

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書誌詳細
主要な著者: Green, Keith D., Chen, Wenjing, Garneau-Tsodikova, Sylvie
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122451/
https://ncbi.nlm.nih.gov/pubmed/21537023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00312-11
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