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Effects of Altering Aminoglycoside Structures on Bacterial Resistance Enzyme Activities
Aminoglycoside-modifying enzymes (AMEs) constitute the most prevalent mechanism of resistance to aminoglycosides by bacteria. We show that aminoglycosides can be doubly modified by the sequential actions of AMEs, with the activity of the second AME in most cases unaffected, decreased, or completely...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Microbiology
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3122451/ https://ncbi.nlm.nih.gov/pubmed/21537023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00312-11 |
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