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Combining Chalcones with Donepezil to Inhibit Both Cholinesterases and Aβ Fibril Assembly

The fact that the number of people with Alzheimer’s disease is increasing, combined with the limited availability of drugs for its treatment, emphasize the need for the development of novel effective therapeutics for treating this brain disorder. Herein, we focus on generating 12 chalcone-donepezil...

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Dades bibliogràfiques
Publicat a:Molecules
Autors principals: Thamban Chandrika, Nishad, Fosso, Marina Y., Tsodikov, Oleg V., LeVine, Harry, Garneau-Tsodikova, Sylvie
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6983213/
https://ncbi.nlm.nih.gov/pubmed/31878304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25010077
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