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Targeting the TLR signalosome with TIR domain-derived cell-permeable decoy peptides: the current state and perspectives

The ability to engineer pharmaceuticals that target the signal-dependent interactions of signaling proteins should revolutionize drug development. One approach to the rational design of protein interaction inhibitors uses decoy peptides, i.e. segments of protein primary sequence, which are derived f...

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Détails bibliographiques
Publié dans:Innate Immun
Auteurs principaux: Toshchakov, Vladimir Y, Javmen, Artur
Format: Artigo
Langue:Inglês
Publié: SAGE Publications 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6974878/
https://ncbi.nlm.nih.gov/pubmed/31955621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1753425919844310
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