Targeting Toll-like Receptor (TLR) Signaling by Toll/Interleukin-1 Receptor (TIR) Domain-containing Adapter Protein/MyD88 Adapter-like (TIRAP/Mal)-derived Decoy Peptides

Toll/interleukin-1 receptor (TIR) domain-containing adapter protein/MyD88 adapter-like (TIRAP/Mal) is an adapter protein that facilitates recruitment of MyD88 to TLR4 and TLR2 signaling complexes. We previously generated a library of cell-permeating TLR4 TIR-derived decoy peptides fused to the trans...

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Detalhes bibliográficos
Main Authors: Couture, Leah A., Piao, Wenji, Ru, Lisa W., Vogel, Stefanie N., Toshchakov, Vladimir Y.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3397892/
https://ncbi.nlm.nih.gov/pubmed/22648407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.360925
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