Identification of Binding Sites for Myeloid Differentiation Primary Response Gene 88 (MyD88) and Toll-like Receptor 4 in MyD88 Adapter-like (Mal)

Upon activation, Toll-like receptor 4 (TLR4) binds adapter proteins, including MyD88 (myeloid differentiation primary response gene 88) and Mal (MyD88 adapter-like) for its signal transduction. TLR4 and the adapter proteins each contain a Toll/Il-1 receptor domain (TIR domain). In this study we used...

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Detalhes bibliográficos
Main Authors: Bovijn, Celia, Desmet, Anne-Sophie, Uyttendaele, Isabel, Van Acker, Tim, Tavernier, Jan, Peelman, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636891/
https://ncbi.nlm.nih.gov/pubmed/23460645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.415810
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