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Inhibition of TLR4 Signaling by TRAM-derived Decoy Peptides in Vitro and in Vivo
Toll/IL-1R domain- (TIR-) containing adapter inducing IFN-β-(TRIF-) related adapter molecule (TRAM) serves as a bridging adapter that enables recruitment of TRIF to activated TLR4 and thereby mediates the induction of TRIF-dependent cytokines. A library of cell-permeating decoy peptides derived from...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3578136/ https://ncbi.nlm.nih.gov/pubmed/23345333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202703 |
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