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Targeting TLR4 Signaling by TLR4 TIR-derived Decoy Peptides: Identification of the TLR4 TIR Dimerization Interface
Agonist-induced dimerization of TLR4 TIR domains initiates intracellular signaling. Therefore, identification of the TLR4 TIR dimerization interface is one key to the rational design of therapeutics that block TLR4 signaling. A library of cell-permeating “decoy peptides,” each of which represents a...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3071460/ https://ncbi.nlm.nih.gov/pubmed/21402890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002424 |
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