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Blocking TIR domain interactions in TLR9 Signaling
Interaction of TLR9 with ligands activates nuclear factor-κB, leading to proinflammatory cytokine production. Excessive TLR activation is a pathogenic factor for inflammatory diseases. This study has examined cell-permeating decoy peptides (CPDPs) derived from the TLR9 Toll-IL-1R Resistance (TIR) do...
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| Опубликовано в: : | J Immunol |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6057823/ https://ncbi.nlm.nih.gov/pubmed/29914886 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1800194 |
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