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Targeting the TLR signalosome with TIR domain-derived cell-permeable decoy peptides: the current state and perspectives

The ability to engineer pharmaceuticals that target the signal-dependent interactions of signaling proteins should revolutionize drug development. One approach to the rational design of protein interaction inhibitors uses decoy peptides, i.e. segments of protein primary sequence, which are derived f...

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Detalhes bibliográficos
Publicado no:Innate Immun
Main Authors: Toshchakov, Vladimir Y, Javmen, Artur
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6974878/
https://ncbi.nlm.nih.gov/pubmed/31955621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1753425919844310
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