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Impact of Classical Strain Improvement of Penicillium rubens on Amino Acid Metabolism during β-Lactam Production

To produce high levels of β-lactams, the filamentous fungus Penicillium rubens (previously named Penicillium chrysogenum) has been subjected to an extensive classical strain improvement (CSI) program during the last few decades. This has led to the accumulation of many mutations that were spread ove...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Appl Environ Microbiol
Main Authors: Wu, Min, Crismaru, Ciprian G., Salo, Oleksandr, Bovenberg, Roel A. L., Driessen, Arnold J. M.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2020
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6974646/
https://ncbi.nlm.nih.gov/pubmed/31757830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01561-19
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