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Molecular mechanism of an antagonistic antibody against glucose-dependent insulinotropic polypeptide receptor

Glucose-dependent insulinotropic polypeptide (GIP) is an incretin hormone involved in regulating glucose and lipid metabolism. GIP receptor (GIPR) antagonism is believed to offer therapeutic potential for various metabolic diseases. Pharmacological intervention of GIPR, however, has limited success...

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Bibliografische gegevens
Gepubliceerd in:MAbs
Hoofdauteurs: Min, Xiaoshan, Yie, Junming, Wang, Jinghong, Chung, Ben C., Huang, Ching-Shin, Xu, Haoda, Yang, Jie, Deng, Liying, Lin, Joanne, Chen, Qing, Abbott, Christina M., Gundel, Caroline, Thibault, Stephen A., Meng, Tina, Bates, Darren L., Lloyd, David J., Véniant, Murielle M., Wang, Zhulun
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2020
Onderwerpen:
Report
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6973313/
https://ncbi.nlm.nih.gov/pubmed/31905038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2019.1710047
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