Molecular mechanism of an antagonistic antibody against glucose-dependent insulinotropic polypeptide receptor

Glucose-dependent insulinotropic polypeptide (GIP) is an incretin hormone involved in regulating glucose and lipid metabolism. GIP receptor (GIPR) antagonism is believed to offer therapeutic potential for various metabolic diseases. Pharmacological intervention of GIPR, however, has limited success...

Descripción completa

Detalles Bibliográficos

Autores principales:	Xiaoshan Min, Junming Yie, Jinghong Wang, Ben C. Chung, Ching-Shin Huang, Haoda Xu, Jie Yang, Liying Deng, Joanne Lin, Qing Chen, Christina M. Abbott, Caroline Gundel, Stephen A. Thibault, Tina Meng, Darren L. Bates, David J. Lloyd, Murielle M. Véniant, Zhulun Wang
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Taylor & Francis Group 2020-01-01
Colección:	mAbs
Materias:	GIPR antagonistic antibody crystallography structure
Acceso en línea:	https://www.tandfonline.com/doi/10.1080/19420862.2019.1710047
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!