Molecular mechanism of an antagonistic antibody against glucose-dependent insulinotropic polypeptide receptor

Glucose-dependent insulinotropic polypeptide (GIP) is an incretin hormone involved in regulating glucose and lipid metabolism. GIP receptor (GIPR) antagonism is believed to offer therapeutic potential for various metabolic diseases. Pharmacological intervention of GIPR, however, has limited success...

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Detalhes bibliográficos
Publicado no:MAbs
Main Authors: Min, Xiaoshan, Yie, Junming, Wang, Jinghong, Chung, Ben C., Huang, Ching-Shin, Xu, Haoda, Yang, Jie, Deng, Liying, Lin, Joanne, Chen, Qing, Abbott, Christina M., Gundel, Caroline, Thibault, Stephen A., Meng, Tina, Bates, Darren L., Lloyd, David J., Véniant, Murielle M., Wang, Zhulun
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
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Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6973313/
https://ncbi.nlm.nih.gov/pubmed/31905038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2019.1710047
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