Molecular mechanism of an antagonistic antibody against glucose-dependent insulinotropic polypeptide receptor

Glucose-dependent insulinotropic polypeptide (GIP) is an incretin hormone involved in regulating glucose and lipid metabolism. GIP receptor (GIPR) antagonism is believed to offer therapeutic potential for various metabolic diseases. Pharmacological intervention of GIPR, however, has limited success...

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Dades bibliogràfiques
Publicat a:MAbs
Autors principals: Min, Xiaoshan, Yie, Junming, Wang, Jinghong, Chung, Ben C., Huang, Ching-Shin, Xu, Haoda, Yang, Jie, Deng, Liying, Lin, Joanne, Chen, Qing, Abbott, Christina M., Gundel, Caroline, Thibault, Stephen A., Meng, Tina, Bates, Darren L., Lloyd, David J., Véniant, Murielle M., Wang, Zhulun
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2020
Matèries:
Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6973313/
https://ncbi.nlm.nih.gov/pubmed/31905038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2019.1710047
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