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PET imaging of mGluR5 in Alzheimer’s disease
BACKGROUND: Metabotropic glutamate subtype 5 receptors (mGluR5) modulate synaptic transmission and may constitute an important therapeutic target in Alzheimer’s disease (AD) by mediating the synaptotoxic action of amyloid-β oligomers. We utilized the positron emission tomography (PET) radioligand [(...
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| Publicado no: | Alzheimers Res Ther |
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| Main Authors: | , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6969979/ https://ncbi.nlm.nih.gov/pubmed/31954399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-020-0582-0 |
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