In vivo evidence for dysregulation of mGluR5 as a biomarker of suicidal ideation

Recent evidence implicates dysregulation of metabotropic glutamatergic receptor 5 (mGluR5) in pathophysiology of PTSD and suicidality. Using positron emission tomography and [(18)F]FPEB, we quantified mGluR5 availability in vivo in individuals with PTSD (n = 29) and MDD (n = 29) as a function of sui...

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Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Davis, Margaret T., Hillmer, Ansel, Holmes, Sophie E., Pietrzak, Robert H., DellaGioia, Nicole, Nabulsi, Nabeel, Matuskey, David, Angarita-Africano, Gustavo, Carson, Richard E., Krystal, John H., Esterlis, Irina
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2019
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561298/
https://ncbi.nlm.nih.gov/pubmed/31085640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1818871116
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