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Preparation of the Metabotropic Glutamate Receptor 5 (mGluR5) PET Tracer [(18)F]FPEB for Human Use: An Automated Radiosynthesis and a Novel One-Pot Synthesis of its Radiolabeling Precursor
The radiotracer 3-[(18)F]fluoro-5-(2-pyridinylethynyl)benzonitrile, or [(18)F]FPEB, is a promising PET imaging agent for the metabotropic glutamate subtype 5 receptor (mGluR5). In an effort to develop a routine production method of this radiotracer for use in clinical research we adapted its radiosy...
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| Publicat a: | Appl Radiat Isot |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4253068/ https://ncbi.nlm.nih.gov/pubmed/25305528 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apradiso.2014.09.006 |
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