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Preparation of the Metabotropic Glutamate Receptor 5 (mGluR5) PET Tracer [(18)F]FPEB for Human Use: An Automated Radiosynthesis and a Novel One-Pot Synthesis of its Radiolabeling Precursor

The radiotracer 3-[(18)F]fluoro-5-(2-pyridinylethynyl)benzonitrile, or [(18)F]FPEB, is a promising PET imaging agent for the metabotropic glutamate subtype 5 receptor (mGluR5). In an effort to develop a routine production method of this radiotracer for use in clinical research we adapted its radiosy...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Appl Radiat Isot
Egile Nagusiak: Lim, Keunpoong, Labaree, David, Li, Songye, Huang, Yiyun
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253068/
https://ncbi.nlm.nih.gov/pubmed/25305528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apradiso.2014.09.006
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