Kinetic analysis of the metabotropic glutamate subtype 5 tracer [(18)F]FPEB in bolus and bolus-plus-constant-infusion studies in humans

[(18)F]FPEB is a positron emission tomography tracer which, in preclinical studies, has shown high specificity and selectivity toward the metabotropic glutamate receptor 5 (mGluR5). It possesses the potential to be used in human studies to evaluate mGluR5 function in a range of neuropsychiatric diso...

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Detalhes bibliográficos
Main Authors: Sullivan, Jenna M, Lim, Keunpoong, Labaree, David, Lin, Shu-fei, McCarthy, Timothy J, Seibyl, John P, Tamagnan, Gilles, Huang, Yiyun, Carson, Richard E, Ding, Yu-Shin, Morris, Evan D
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3618388/
https://ncbi.nlm.nih.gov/pubmed/23250105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2012.195
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