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Synthesis of phosphonoacetate analogues of the second messenger adenosine 5′-diphosphate ribose (ADPR)

Adenosine 5′-diphosphate ribose (ADPR) is an intracellular signalling molecule generated from nicotinamide adenine dinucleotide (NAD(+)). Synthetic ADPR analogues can shed light on the mechanism of activation of ADPR targets and their downstream effects. Such chemical biology studies, however, are o...

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Detalles Bibliográficos
Publicado en:RSC Adv
Autores principales: Baszczyňski, Ondřej, Watt, Joanna M., Rozewitz, Monika D., Fliegert, Ralf, Guse, Andreas H., Potter, Barry V. L.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Royal Society of Chemistry 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6957348/
https://ncbi.nlm.nih.gov/pubmed/31934327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9ra09284f
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