Caricamento...
Novel Deazaflavin Tyrosyl-DNA Phosphodiesterase 2 (TDP2) Inhibitors
Tyrosyl-DNA phosphodiesterase 2 (TDP2) is a DNA repair enzyme that removes 5′-phosphotyrosyl blockages resulting from topoisomerase II (TOP2)-DNA cleavage complexes trapped by TOP2 inhibitors. TDP2 is a logical target for the development of therapeutics to complement existing treatments based on inh...
Salvato in:
| Pubblicato in: | DNA Repair (Amst) |
|---|---|
| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6952553/ https://ncbi.nlm.nih.gov/pubmed/31775111 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2019.102747 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|